Breast implant-associated lymphoma: what a radiologist should know.

Congress:

ECR 2018

Poster Number:

C-3245

Type:

Educational Exhibit

Keywords:

Lymph nodes, Breast, Oncology, CT, Ultrasound, PET-CT, Diagnostic procedure, Prostheses, Cancer, Haematologic diseases

Authors:

E. Pace, A. Wotherspoon, A. Attygalle, S. Iyengar, B. sharma; London/UK

DOI:

10.1594/ecr2018/C-3245

DOI-Link:

https://dx.doi.org/10.1594/ecr2018/C-3245

Table 2: Patients with breast implant associated anaplastic large T-cell lymphoma...

Fig. 3: CASE 1 - 42-year-old woman who had had bilateral breast augmentation in 2003. ...

Fig. 4: CASE 1 - IMMUNOHISTOCHEMISTRY: The infiltrate was CD30 positive

Fig. 5: CASE 2 - 29-year-old woman who had had bilateral breast augmentation (transform...

Fig. 6: CASE 2 - HISTOLOGY: The infiltrate of large atypical cells was seen to...

Fig. 7: CASE 3 - 50-year-old lady with right mastectomy and axillary node clearance...

Fig. 8: CASE 3 - HISTOLOGY: Cytology sample of seroma fluid showed large anaplastic...

Fig. 9: CASE 4 - 49-year-old woman who had Poly Implant Prostheses silicone breast...

Fig. 10: CASE 4 - IMMUNOHISTOCHEMESTRY: The infiltrate was CD30 positive.

Fig. 11: CASE 5 - 39-year-old lady, BRCA2 mutation carrier. In 2004 she had had...

Fig. 12: CASE 5 -HISTOLOGY: The capsulectomy specimen exhibited a dense infiltrate of...

Fig. 13: CASE 6 - 55-year-old lady. In 2000, she was diagnosed a right breast...

Fig. 14: CASE 6 - IMMUNOHISTOCHEMESTRY: The infiltrate was positive for CD30, CD2. and...

Fig. 15: CASE 7 - 50-year-old lady. In 2010 she had had left breast cancer (HER2...

Fig. 16: CASE 7 - HISTOLOGY of capsulectomy specimen displayed a dense infiltrate of...

Findings and procedure details

At our oncological hospital, 7 women, between 29 and 55 years old, were referred with BI-ALCL between 2015 and 2017. We retrospectively reviewed imaging and pathology of these cases to highlight pathognomonic features.

Furthermore, type and texture of implant along with the onset of the lymphoproliferative disease after surgery were also assessed (table 2).

Hereafter our most explicative and/or challenging cases (1-7) are illustrated.