Keywords:
Head and neck, Thyroid / Parathyroids, CT, Audit and standards, Endocrine disorders
Authors:
L. M. Loy1, S. W. Kheok2, L. E. McAdory2; 1SINGAPORE, SINGAPORE/SG, 2Singapore/SG
DOI:
10.26044/ecr2019/C-0206
Aims and objectives
Primary hyperparathyroidism (PHP) is characterized by hypercalcemia caused by 1 or more hyperfunctioning parathyroid glands.
Single gland parathyroid adenomas are the cause in 75-85% of cases,
with the remaining cases due to double gland lesions and hyperplasia.
[1,
2] Definitive treatment is surgical resection of the hyperfunctioning glands.
Accurate pre-operative localization,
usually with sestamibi and ultrasound (US) scans,
allows the resection to be done using focused or unilateral parathyroidectomy instead of 4-gland exploration.
[2,
3]
4-dimensional computed tomography (4D CT) has been reported to be a more sensitive and accurate alternative method for pre-operative localization of hyperfunctioning parathyroid glands.[4,
5] Several studies on Caucasian patients also suggested that 4D CT could provide positive localization in patients who previously had negative or discordant sestamibi and US results.
[2,
6,
7]
The aim of our study is to audit the performance of 4D CT in localizing primary parathyroid lesions in Asian patients.