Type:
Educational Exhibit
Keywords:
Oncology, CT, PET-CT, SPECT, Computer Applications-Detection, diagnosis, Computer Applications-General, Neoplasia, Cancer
Authors:
P. Asokan1, S. S. Shivalingappa2, I. DESAI2, M. Kumar3, A. Kesari4, S. Sampangi2; 1560027/IN, 2Bangalore, Karnataka/IN, 3BIKANER/IN, 4Bangalore/IN
DOI:
10.26044/ecr2019/C-0292
Background
Neuroblastoma tumours of ganglion cell origin that derive from primordial neural crest cells,
which are the precursors of the sympathetic nervous system.
Most common extracranial solid pediatric malignancy.
Peak incidence at age of 2–3 years
- Neuroblastoma arise from the adrenal glands,
the organ of Zuckerkandl or along the distribution of the sympathetic ganglia in paraspinal areas from the neck to the pelvis.
- The most common primary site for NBL development is the retroperitoneum,
the adrenal medulla (35%) and the extra-adrenal paraspinal ganglia (30%– 35%),
followed by the mediastinum in 20%,
pelvis (2%–3%),
(1%–5%).
Unusual primary locations such as thymus,
lung,
kidney,
anterior mediastinum.
Imaging plays an important role in the diagnosis,
staging,
treatment planning,
response evaluation and in follow-up of a case of Neuroblastoma.