Keywords:
Cardiovascular system, Contrast agents, Veins / Vena cava, CT, Catheter venography, Contrast agent-intravenous, Obstruction / Occlusion
Authors:
C. H. Kristiansen1, T. Tran2, J. C. Lindstrom1, H. Ashraf3, P. Lauritzen2; 1Lørenskog/NO, 2Oslo/NO, 3RASTA/NO
DOI:
10.26044/ecr2019/C-1492
Aims and objectives
The most important patient factors determining enhancement effect of contrast agents are weight and cardiac output [1].
Tailoring the dosage of contrast agents to individual patients is usually achieved by a linear or stepwise increase in dosage according to body weight.
This approach is imprecise,
especially for obese patients,
since adipose tissue does not contribute substantially to contrast distribution [2-4].
Axial CT images of one obese and one average patient is shown in figure 1.
Tailoring contrast agent dosage to lean body mass (LBM) is more precise and may result in less variation in enhancement between patients [4-7].
Between the mid-sixties and the mid-eighties three acknowledged mathematical formulas to estimate LBM from age,
sex,
height and weight were developed by James,
Hume and Boer,
respectively [8-10].
LBM may also be estimated by bioelectrical impedance analysis (BIA).
BIA measures conductance through the body tissue by applying a constant,
low level,
frequency-dependent electrical current.
Because it is relatively inexpensive,
non-invasive and require little technical expertise,
estimation of LBM based on BIA is becoming more commonplace [11].
BIA is,
by some,
considered the reference standard in body composition evaluation [3].
We aim to validate a portable BIA device against acknowledged formulas (Boer,
James,
Hume) for estimation of LBM.