This study highlighted that females had accelerated atrophic changes (upto 30%) and as early as 42 years whereas  males showed atrophic changes (upto 17%) as late as 50 years of age. The study indicates that females are more suscpetible to early atrophic changes with higher frequency in age group of 40-50 compared to males. In conclusion the age brackets for Dementia screeening needs to be revised and adjusted not just by age but also by gender to detect earlier changes with the help of volumetric analysis.