Keywords:
Head and neck, Paediatric, Trauma, MR, MR-Functional imaging, Statistics
Authors:
M. Ublinskiy, N. Semenova, T. Akhadov, P. E. P. Menshchikov, A. Manzhurtsev, I. Melnikov, M. Akhlebinina; Moscow/RU
DOI:
10.26044/ecr2019/C-1834
Aims and objectives
Mild traumatic brain injury (mTBI) occupies one of the first places in children injuries.
Patients with mTBI may suffer headache,
dizziness memory loss and short-term loss of consciousness in acute stage of injury [1].
However,
in patients with mTBI there is usually an absence of structural lesions revealed by MRI studies in particular.
That’s why mTBI neurobiological mechanisms are not fully understood.
Resting-state functional MRI (rsfMRI) allows us to obtain new information on functional connectivity patterns of human brain.
This technique is especially useful to reveal functional network disturbances in cases of MR normal-appearing structures.
Among all brain networks at the resting state, Default Mode Network (DMN) is the most widely studied network [2].
The revealed important role of DMN in cognitive processes and its disruption in different neurocognitive disorders makes the study of DMN functional integrity in patients with mTBI very useful.
Aim of this study is to examine functional connectivity in normal-appearing cortex in acute period of mild traumatic brain injury (mTBI) using resting state functional (rsfmRI).