Keywords:
Head and neck, Paediatric, Trauma, MR, MR-Functional imaging, Statistics
Authors:
M. Ublinskiy, N. Semenova, T. Akhadov, P. E. P. Menshchikov, A. Manzhurtsev, I. Melnikov, M. Akhlebinina; Moscow/RU
DOI:
10.26044/ecr2019/C-1834
Methods and materials
Patients: 34 MR negative participants were studied in age from 12 to 17 years (mean age – 14.5 years).
Group of patients consisted of 17 children with mild traumatic brain injury in acute stage.
17 age-matched healthy volunteers comprised control group.
Materials and methods:
All studies were performed at Phillips Achieva 3.0T MRI scanner using 32-channel head coil.
fMRI studies were conducted using EPI BOLD (TR = 3000,
TE = 30,
EPI factor = 240,
slice thickness = 4 mm,
NSA = 1,
80 dynamics,
total duration – 4 minutes).
For each participant fMRI performing was repeated twice.
fMRI data were processed using functional connectivity toolbox CONN [3].
Seed-based analysis was performed in order to reveal disturbances in functional connectivity.
Statistical processing was performed using software package Statistica 12 using Mann-Whitney criterion to evaluate statistical intergroup differences..