Keywords:
Genital / Reproductive system male, Oncology, MR-Diffusion/Perfusion, Diagnostic procedure, Biopsy, Cancer, Outcomes
Authors:
S. Verna1, S. Agostini1, E. Bertelli1, F. Parretti1, S. Lucarini1, F. De Nisco1, M. Mastrorosato1, L. N. Mazzoni2, V. Miele1; 1Florence/IT, 2Pistoia/IT
DOI:
10.26044/ecr2019/C-2497
Results
Fusion-targeted biopsy was positive for PCa in 28/43 lesions (Group A),
23/28 showing a Gleason Score (GS)≥3+4,
with mean±SD ADC value of 715±130x10-6×mm2/s and negative in 15/43 lesions (Group B) with mean±SD ADC value of 879±67x10-6×mm2/s.
T-test showed significant lower ADC values in group A compared with group B (p-value<0.01).
Fig. 4: Apparent Diffusion Coefficient (ADC) scatterplot of peripheral zone lesions classified as PIRADSv2 4, respectively positive and negative for prostate cancer at biopsy. It can be seen that tissues positive for prostate cancer show lower ADC values.
Fig. 5: Apparent Diffusion Coefficient (ADC) histogram (mean±standard deviation) of peripheral zone lesions with PIRADSv2 4, respectively positive and negative for prostate cancer at biopsy. It can be seen that tissues positive for prostate cancer show lower ADC values.
In PI-RADSv2 4(3+1) subgroup,
5/14 suspected lesions were positive for PCa (GS≥3+4 in 3 cases),
with mean±SD ADC value of 726±89x10-6×mm2/s and 9/14 lesions were negative for PCa with mean±SD ADC value of 888±58x10-6×mm2/s.