Keywords:
Paediatric, Oncology, CT, PET-CT, Staging, Lymphoma
Authors:
K. Khasanova, I. E. Tyurin, V. Sinitsyn; moscow/RU
DOI:
10.26044/ecr2019/C-3143
Methods and materials
Patient population: 77 pediatric patients (mean age 13.8+-4.2 years) with histologically proven HL underwent pretreatment full body CE CT followed with 18F-FDG-PET/CT (not later than two weeks after CT) as a part for the initial staging of the disease.
Exclusion criteria: patients with pathological lymphadenopathy caused not by the lymphomatous process:
- primary immunodeficiency(PID),
- sarcoidosis
- tuberculosis
Lymphomatous involvment:
On CT
1. Lymph nodes with short axis greater then 10mm,
or long axis greater then 15mm
2. Pathological contrast enhancement of parenchymal organs
3. Consolidation origins and multiple nodules in lungs
4. Litic or blastic lesions of bones
On 18F-FDG PET/CT - all regions with pathologicall FDG metabolism were considered as limphomatous process.
Fifteen anatomic regions have been analyzed: 10 nodal and 5 extranoda (table1).
All findings were correlated with results of clinical follow-up or biopsy.