Keywords:
Not applicable, Prospective, Lymphoma, Haematologic diseases, Imaging sequences, MR-Diffusion/Perfusion, MR, Oncology, Musculoskeletal bone, Haematologic, Oncologic Imaging, Performed at one institution
Authors:
N. Lutsik, G. Yatsyk, L. Mendeleeva, M. Solovev, V. Savchenko; Moscow/RU
DOI:
10.26044/ecr2020/C-03990
Methods and materials
Patient population: 14 patients (5 M/9 F, median age 55 years; range: 33-71 years) with newly diagnosed, untreated multiple myeloma, plasmacytoma, and plasmablastic lymphoma were included in the study between January 2019 and October 2019. 12 patients had multiple myeloma, 1 patient had plasmacytoma and 1 patient had plasmablastic lymphoma.
Data acquisition: Whole-body MRI with DWIBS imaging was conducted on a 1.5 T scanner (Ingenia, Philips, Netherlands). Patients were placed in a spine position. The whole-body MRI protocol included DWIBS with 3 b-values (0, 500, 1000 s/mm²), coronal and sagittal T1SE and STIR, axial T2SE.
Data analysis: 7 patients had a focal pattern of bone marrow infiltration, 2 patients had a diffuse pattern, 2 patients had a variegated pattern and 3 patients had a normal pattern of bone marrow. For the focal pattern of infiltration, ADC was calculated placing an ROI in several focal lesions of bone marrow infiltration, the highest ADC value was recorded. For diffuse and variegated patterns, ROI measurements were obtained from scull, femurs, humerus, C4, Th6, L3 vertebrae, sacrum and ilium, the mean ADC value was calculated.