1-RB-ILD:
Case-1 : 45 y.o.a male/smoker with 80 pack-year/non-productive cough/exertional dyspnea for last 6 months. CT findings are consistent with RB-ILD (Figure-1).
2-DIP:
Case-2 : 43 y.o.a female-patient with 25 pack-year smoking history/complaining non-productive cough/finger clubbing. CT findings are consistent with DIP (Figure-2).
3-PLCH:
Case-3 : 58 y.o.a male/smoker with 50 pack-year history, with the complaints of clubbing/dyspnea. CT findings are consistent with PLCH (Figure-3).
4-IPF:
Case-4 : 75 y.o.a male/smoker with dyspnea. Lung auscultation reveals velcro crackles in bilateral lung bases. CT shows typical findings for UIP pattern (Figure-4). After clinical/laboratory examinations, patient is diagnosed as “Idiopathic pulmonary fibrosis”.
5-CPFE:
Case-5 : 78 y.o.a male/smoker with 40 pack-year smoking history complaining about dyspnea/non-productive cough. CT shows typical findings for CPFE (Figure-5).
6-Others:
6a-PAP:
Case-6 : 20 y.o.a non-smoker male/patient with fever/sweating/progressive lung infiltrations on chest X-ray despite proper antibiotic treatment. Although patient is non-smoker, his CT findings are typical for PAP, so we decided to use his CT images to discuss expected imaging findings of PAP (Figure-6).
6b-G-DAH:
Case-7 : 26-year-old male/patient with 4 pack-years of smoking history,presented to hospital with nausea-vomiting/extensive edema. As result of examinations, it was found that symptoms were due to nephrotic syndrome, renal biopsy revaled diagnosis of anti-GBM disease. During follow-up, acute respiratory failure with rapid hemoglobin decline developed, patient was transferred to intensive care unit. Two CT scans obtained at approximately 1.5 month apart show significant progression of findings suggesting diffuse alveolar hemorrhage secondary to Goodpasture syndrome (Figure-7).
6c-RA-ILD:
Case-8 : 59-year-old male/patient with 30 pack-years of smoking history, followed-up rheumatoid arthritis for 21 years. CT reveals interstitial lung disease/typical rheumatoid nodules (Figure-8:A-B).
Case-9 : The patient with history of 30 pack-years of smoking/followed-up for 18 years for rheumatoid arthritis underwent further examination for complaints of dyspnea/walking difficulty/swelling of legs. Examinations revealed pulmonary hypertension/right heart failure (Figure-8:C-D).
Case-10 : A 62-year-old female-patient with dry cough/followed up for rheumatoid arthritis. CT findings are in favor of non-specific interstitial pneumonia (NSIP) pattern (Figure-8:E-F). Although patient did not smoke, this case was included because NSIP pattern is second most common pattern in RA-ILD. The most common pattern in RA-ILD is UIP. However, as imaging findings of UIP were examined in Figure 4, it was not discussed here.
6d-AEP:
Case-11: A 24-year-old male/patient admitted to hospital with complaints of dyspnea/weakness,diagnosed as aplastic anemia,underwent bone marrow transplantation, needed intensive care for acute respiratory failure. During follow-up, ARDS developed in short time,patient died before opportunity for further evaluation. This case was included because there were radiological findings that could be observed in AEP (Figure-9). Since radiological findings of acute eosinophilic pneumonia, hydrostatic pulmonary edema, ARDS, acute interstitial pneumonia, atypical viral/bacterial pneumonias are very similar, clinical criteria/laboratory findings are important for differential diagnosis. Most of aforementioned diseases are acute/rapidly progressive, so they mostly require immediate intervention, intensive care. It is not always possible to have adequate time for making differential diagnosis.