Keywords:
Performed at one institution, Experimental, Retrospective, Cancer, Technical aspects, CT, Respiratory system, Chest
Authors:
I. Blokhin, V. Gombolevskiy, O. Minkina, V. Chernina, A. Nikolaev, A. P. Gonchar, S. Morozov; Moscow/RU
DOI:
10.26044/ecr2020/C-11458
Methods and materials
We retrospectively analyzed 63 inspiratory-expiratory ULDCT scans performed as a part of the pulmonary emphysema screening subgroup. Moscow Lung Cancer Screening trial inclusion criteria were as follows:
- aged from 50 to 75 years
- asymptomatic (excluding smoking-related cough, sputum, dyspnoea)
- pack-year index > 20
The exclusion criteria were as follows: younger than 50 years or older than 75 years, pack-year index < 20, smoking cessation > 10 years ago, chest pain, body temperature > 37.5 C, hemoptysis, pink sputum, inexplicable weight loss, hoarse voice, less than 30 days since recovery from an illness, lung cancer or metastatic lung lesions or underwent routine chest CT in last year.
The audit of images and reports showed that all nodules were classified as benign (i.e., LR-2 or LR-3) per Lung-RADS (2014) classification. Solid pulmonary nodule volume was measured semi-automatically through seed placement on the Syngo.via workstation with the calculation of volume delta and mean diameter. We excluded 33 scans due to poor image quality, small nodule size (<2 mm), perifissural location, or gross volume measurement errors.