Sclerosing Angiomatoid Nodular Transformation of the Spleen- A Single-Center Retrospective Review

Congress:

ECR 2021

Poster Number:

C-12774

Type:

Scientific Exhibit

Keywords:

Abdomen, Spleen, CT, MR, Ultrasound, Education, Cancer

Authors:

A. Yousaf¹, H. M. Fazeel², S. S. Batool³, A. L. F. Yasin¹, M. A. H. Shah¹; ¹Doha/QA, ²New York, NY/US, ³Alabama, AL/US

DOI:

10.26044/ecr2021/C-12774

DOI-Link:

https://dx.doi.org/10.26044/ecr2021/C-12774

Conclusion

From our study results and review of the literature, we conclude that Splenic SANT is a benign neoplasm of the spleen that usually presents as a solitary mass with no reported case of recurrence after surgical resection.
The most consistent findings on the US: hypoechoic with internal vascularity, CT: Hypodense lesion with a progressive filling of the lesion through the arterial, venous, and delayed phase, MRI: T1WI: Iso-hyperintense, T2WI: Hypointense signals (The most reliable/consistent), DWI: Hypointense, Gd Contrast enhancement: Progressive centripetal enhancement, central non-enhancing focus and variable density/intensity bands in the lesion were also found.
Although there is no bigger study of imaging features correlating immunohistochemistry of the splenic lesions, we propose that the asymptomatic patients with stable lesions and typical imaging features should be offered conservative management with a routine follow-up, and a surgical approach should only be considered if the patient is symptomatic or the evolving size or imaging features are found.
This study and literature review also emphasizes the need for a multicenter study to further validate these typical imaging findings with the immunohistochemical features of the lesion.

Fig 1: Figure 2: A 50-old female presented with on & off left upper quadrant abdominal...

Fig 2: Figure 2: A 42-year-old man presented with vague abdominal symptoms. US...

Fig 3: A 26-year-old female presented with left upper abdominal pain. CT of the...

Fig 4: Figure 4: Gadolinium enhanced MRI Abdomen (same patient in figure 3) The...

Fig 5: Figure 4: Gadolinium enhanced MRI Abdomen (same patient in figure 1) The...

Fig 6: Table 1: Patients Demographics and Imaging Features

Fig 7: Table 2A: Literature Review (2011-2020)(Continuous...) Abbreviations: F:...

Fig 8: Table 2B: Literature Review (2011-2020) Abbreviations: F: female, M: male,...

Fig 9: Table 3: Analysis of Published Case Reports between 2011-2020