Contrast –Enhanced Ultrasound (CEUS) neovascularisation diagnostic limitation in unstable atherosclerotic plaque with extensive calcified component

Congress:

ECR 2021

Poster Number:

C-13610

Type:

Scientific Exhibit

Keywords:

Cardiovascular system, CT-Angiography, Ultrasound, Ultrasound-Colour Doppler, Comparative studies, Contrast agent-intravenous, Thrombolysis, Arteriosclerosis

Authors:

A. Lioznovs, M. Radzina, S. Pavlovics, L. Saule, J. Savlovskis, A. Lacis, D. Krievins; Riga/LV

DOI:

10.26044/ecr2021/C-13610

DOI-Link:

https://dx.doi.org/10.26044/ecr2021/C-13610

Results

Unstable plaque was diagnosed in 73 patients using Duplex US method and in 74 patients using CT method. Comparing both methods statistically significant correlation was found (rs = 0.781; p = 0.0001). Comparing 2 groups: soft plaques neovascularisation by CEUS was diagnosed in 33 cases (16 cases with Grade1 and 17 - Grade 2).

Fig 6: Comparison of CEUS grading and postoperative histology results. Statistically...

Comparing results with histology - sensitivity was 77.78%, specificity 60%, positive predictive value 77.78%, negative predictive value 71.52%, accuracy 76.3%; In a group with extensive calcified plaques - neovascularisation was detected in 9 patients (52.9%), methods sensitivity 53.4%, specificity 36.5%, positive predictive value 64.54%, negative predictive value 31.4%, accuracy 47.83%, respectively.

Fig 8: Neovascularisation detection sensitivity and specificity in group with soft and...

Comparing CEUS method and results of histology statistically significant correlation was found (rs = 0.61; p = 0.002). Comparing results with CEUS grading and contrast arrival time, was found statistically significant difference between groups (p=0.035) with earlier vasa vasorum enhancement in Grade 2 subgroup.

Fig 7: Comparison of CEUS grading and contrast arrival time. Significant difference...

Fig 1: Histology specimen. Image of carotid aterosclerotic plaque with fibrosis and...

Fig 2: CEUS/B mode side by side US image. Calcified atherosclerotic plaque at internal...

Fig 3: CEUS/B mode side by side US image. Grade 0 neovascularization within carotid...

Fig 4: CEUS/B mode side by side US image with maximum intensity pixel projection mode....

Fig 5: CEUS image. Atherosclerotic carotid plaque with ulceration and Grade 1...

Fig 6: Comparison of CEUS grading and postoperative histology results. Statistically...

Fig 7: Comparison of CEUS grading and contrast arrival time. Significant difference...

Fig 8: Neovascularisation detection sensitivity and specificity in group with soft and...