Keywords:
Neuroradiology brain, MR, PET, SPECT, Education, Seizure disorders
Authors:
P. Sharma, A. Coulthard
DOI:
10.26044/ranzcr2022/R-0222
Purpose
The purpose of this poster is to present a rare case of subcortical band heterotopia (SBH) in a male patient with mosaic doublecortin (DCX) gene mutation.
- SBH, or double cortex syndrome, is a neuronal migration disorder, which occurs very rarely in males [1].
- The syndrome is usually associated with mutations in the DCX (Xp22.3-q23) gene, and much less frequently in the LIS1 (17p13.3) gene [1].
- Typical magnetic resonance imaging (MRI) findings include bands of grey matter situated between the lateral ventricles and the cerebral cortex separated by a layer of normal white matter. Overlying cortex may be normal or pachygyric [2-3].
The poster will explore the patient’s presenting complaint and clinical examination along with discussing relevant imaging findings.