The reconstruction of internal carotid artery (ICA) stenosis is an effective method to reduce stroke risk. The indication for surgery is the presence of a significant grade ICA diameter stenosis (above 70%). According to the international literature in association with surgery the perioperative stroke risk is under 3-2%, whereas the stroke risk in case of significant stenosis is 0.7-1.1%/year in asymptomatic and 20-25%/5 years in symptomatic patients (Halliday et al. 2010; Rothwell et al. 2004). Latest ESVS guideline recommends intervention for asymtomatic patients with higher...

In our prospective study at Semmelweis University, Heart and Vascular Center between January 2016 and May 2017 out of the total of 476 surgical carotid artery reconstruction patients 60 (23 female, 37 male) were included. Inclusion criteria were the informed consent, age under 75 years, adequate quality preoperative carotid CTA with Philips Briliance iCT 256 scanner and preoperative cranial MRI with Philips Achiva 1.5T. CTA analysis: The CTA images of the plaques were analysed with the Medis AngioQ software by two independent observers. For plaque...

During the study period 60 patients fulfilled all enrollment criteria. Patients' characteristics N: 60 Mean age (y) 65.59 +/- 6,67 Female gender (n) 37 Diabetes 45% Hypertension 73.3% Current smoking 32.8% Asymptomatic 86.6% Stroke 6.6% TIA 5% Amaurosis fugax 3.3% There was no interobserver difference between the two observers in either the CTA or the MRI interpretation. For further analysis the second CTA segmentation data was used. The segmented lesions were located in the bifurcation in 73.3%. Positive remodeling was found in 60%. There was...

With the Medis AngioQ semiautomatic software we could effectively and simply perform the qualitative assessment of carotid artery plaques with good reproducibility. Although validation with the gold standard histological samples was not done. Our results suggest that the higher ratio of necrotic components seen on CTA could increase the incidence of relevant side cerebral ischaemic lesions. Thus indication for intervention could not only be based on stenosis grade but also on plaque characteristics.

Alexisz Panajotu, MD Semmelweis University, Heart and Vascular Center, Department of Diagnostic Radiology - Budapest, Hungary 1122 Budapest Határőr út. 18. Phone: +36208259099 E-mail: [email protected]

Fazekas F, Chawluk JB, Alavi A et-al. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR Am J Roentgenol. 1987;149 (2): 351-6. Halliday A, Harrison M, Hayter E, Kong X et al 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1). Lancet 2010;376:1074–1084. Károlyi M, et al Iterative model reconstruction reduces calcified plaque volume in coronary CT angiography. Eur J Radiol. 2017. Naylor AR, JB Rocco, GJ de Borst, S Debus et al Management of Atherosclerotic Carotid and Vertebral...