Learning objectives
* To know a compilation of diseases for which a certitude diagnosis can be established on the basis of the imaging data and the clinical context of the patient.
* To know through practical clinical cases their aspects in imaging
* To know the pearls of "Aunt Minnie" which are going to be described as "keywords" after every clinical case.
Background
* This atlas of “Aunt Minnie” is designed as a practical educational tool which explains to the readers,
some Neuro-radiological cases,
of which the imaging can be typical.
* However,
medicine is not an exact science,
and there are many pitfalls that must be known.
* The reader has to understand that every case must be analyzed in its context by considering diagnostic probabilities and trying to avoid the pitfalls.
Findings and procedure details
1. Close-lipped schizencephaly ( Fig. 1 Fig. 2 ) :
Schizencephaly may be close or open-lipped,
uni or bilateral,
and typically manifests with seizures and mental retardation.
It is a disorder of neuronal migration caused by second-trimester insult or genetics leading to a full-thickness communication between the pia and ventricular system ependyma.
The cleft is lined by abnormal gray matter,
which may act as a seizure focus.
If the abnormal gray matter is closely apposed,
the anomaly is close-lipped; if unopposed,
it is open-lipped.
The...
Conclusion
The maineducational objective of this work isto introduce the residentto a compilation of diseaseor conditions in which a confident diagnosis can
be rendered based on the imaging findings and interpreted in the context of the patient's clinicalpresentation.
References
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Osborn AG,
Blaser SI,
Castillo M,
et al.
Congenital malformations. In: Osborn AG,
Blaser SI,
Castillo M,
et al.
(eds.).
Diagnostic imaging: Brain.
Salt Lake Oty: Amyrsis,
2004:1-1-4--I-1-119.
2.
Oh KY,
Kennedy AM,
Frias AE,
et al.
Fetal schizencephaly: Pre-and postnatal imaging with a review of the clinical manifestations.
Radiographies 2005;25:647--657.
3.
Barkovich JA.
Morphologic characteristics of subcortical heterotopia: MR imaging study.
AJNR Am J Neuroradiol 2000; 21:290-295.
4.
Mitchell LA,
Simon EM,
Filly RA,
et al.
Antenatal diagnosis of subependymal heterotopia.
AJNR AmJ...