Aims and objectives
Juvenile angiofibroma (JAF) is a highly vascular benign tumor of head and neck,
found mainly in adolescent males originated from the superior margin of the sphenopalatine foramen,
usually spread to the pterygopalatine and infratemporal fossae (1).
Intracranial extension of (JAF) occurs in 20 to 36% of patients and is almost always extradural (2).
Tumor extension can occur to the middle cranial fossa and to much lesser extent to anterior cranial fossa.
Extension to the middle cranial fossa can occur via the superior and inferior orbital...
Methods and materials
This study is a retrospective one,
where analysis of the clinical data of 20 adolescent males with radiologically documented and histologically proven juvenile angiofibroma was performed.
Their ages ranged from 6 to 20 years with a mean age of 14.6 years. All patients were treated surgically in the period from January 1997 to March,
2015.
Angiography and embolization procedures were carried out in the angiography and interventional unit.
Radiology Department,
Mansoura University Hospital,
Mansoura,
Egypt.
A written consent was obtained from one of the parents...
Results
Clinical data:
This study included 20 male patients (mean age ± SD: 14.6 ± 7.2 years) with Juvenile angiofibroma and intracranial extensions.
The different clinical presentation is outlined in table (1).
Tumor extension and staging:
Tumor staging was determined by review of the physical examination and imaging studies including CT and MRI for all patients.
Extension of tumor into the middle cranial fossa was seen in 19 patients (95 %) [Right side in 11 (55 %) and left side in 8 (40 %)],
while tumor...
Conclusion
Preoperative embolization of JAF with intracranial extension is useful in reducing the intraoperative blood loss and lowers the risk of tumor recurrence particularly in patients with large intracranial component.
We recommend it as a routine preoperative adjunct in all patients of JAF with intracranial extension,
however meticulous technique plus detailed analysis of the lesion and its vascular supply is a necessityfor safe embolization procedure.
Personal information
T.
Amer,
A.
Elmokadem,
A.
Abdel Khalek
Department of Diagnostic and Interventional Radiology,
Mansoura University,
Mansoura-Egypt.
References
1- Bales C,Kotapka M,Loevner LA,
et al.
Craniofacial resection of advanced juvenilenasopharyngealangiofibroma.
Arch Otolaryngol Head Neck Surg.2002 Sep;128(9):1071-8.
2- El-Banhawy OA,
Ragab A,El-Sharnoby MM.
Surgicalresectionof type IIIjuvenileangiofibromawithout preoperative embolization.
Int J Pediatr Otorhinolaryngol.2006 Oct;70(10):1715-23.
3- Andrews JC,Fisch U,Valavanis A,
et al.
The surgical management of extensivenasopharyngealangiofibromas with the infratemporal fossa approach.
Laryngoscope.1989 Apr;99(4):429-37.
4- Radkowski D,McGill T,Healy GB,
et al.
Angiofibroma.
Changes in staging and treatment.
Arch Otolaryngol Head Neck Surg.1996 Feb;122(2):122-9.
5- Lee JT,Chen P,Safa A,
et al.
Theroleofradiationin thetreatmentofadvancedjuvenile angiofibroma.
Laryngoscope.2002 Jul;112(7 Pt...