Learning objectives
1.
To present a pictorial review covering a range of imaging featuresof common congenital intracranial tumors depicted in infants that were referred to our department.
2.
To demonstrate the contribution of pregnancy and screening ultrasound (US),
multidetector computerized tomography (MDCT) and magnetic resonance imaging (MRI) in providing assessment of the origin and the extent of the tumor,
the invasion of neighboring organs.
3.
To discuss the directcorrelation of theimaging appearancewith the pathologicappearance incongenital intracranialneoplasms.The pathological report is included where relevant.
Background
Primary central nervous system (CNS) tumors are a common group of neoplasms in the pediatric population,
being second only to leukemia in frequency.
CNS tumors of the fetus represent only 10% of all antenatal tumors,
ranking behind extracranial teratomas,
neuroblastomas,
and soft-tissue tumors.
Intracranial teratoma is the most common fetal brain tumor,
accounting for approximately half of all reported cases.
It is followed in frequency by astrocytomas of varying grades,
lipomas,
choroid plexus papillomas,
craniopharyngiomas,
and primitive neuroectodermal tumors.
With regard to anatomic distribution,
the...
Imaging findings OR Procedure details
Our patients have generally undergone US and/or MRI.
We have performed also CT in a few selected cases.
Case 1: B,
female patientpresented to our Unit at the age of 10w,with macrocephalus.
We performed transfontanellar US (that depicted progressive hydrocephalus),
followed by cerebral MRI.
This imaging study revealed a highly vascularised mass that originated in the choroid plexus of the right lateral ventricle and important enlargement of the lateral ventricles.
Fig. 1
Fig. 2
Fig. 3
The HP diagnosiswas choroid plexus papilloma.
She underwent surgical...
Conclusion
1.
Congenital CNS tumors have apoor overall prognosis because of the rapid evolution and the ability of CSF spread.
The diagnosis is often associated with high mortality rate.
2.
The importance of imaging is to establish the tumoral extension as well as to differentiate between the posible curable tumors (such as choroid plexus papiloma) and the fatal outcome tumors.
3.
US is the gold standard for fetal evaluation.
Fetal MRI plays an important role in case of pregnancy and therapeutical management.
US and MRI have...
References
1.
Paula J.
Woodward,
Roya Sohaey,
Anne Kennedy,
Kelly K.
Koeller,
Capt,
MC,
USN.
From the Archives of the AFIP A Comprehensive review of Fetal Tumors with Pathologic Correlation.
RadioGraphics 2005; 25:215–242.
2.Aguzzi A,
Brandner S,
Paulus W.
Choroid plexustumours.
In: Kleihues P,
Cavenee W,
eds.
Pathologyand genetics of tumours of the nervous system.
Lyon,
France: IARC,
2000; 84–86.
3.
Ellenbogen R,
Winston K,
Kupsky W.
Tumors ofthe choroid plexus in children.
Neurosurgery1989; 25:327–335.
4.
Kahn E,
Luros J.
Hydrocephalus from overproductionof cerebrospinal fluid.
J...
Personal Information
I.
Popescu Department of Radiology,
FundeniClinical Institute,
258 Sos Fundeni ,
Bucharest,
Romania.
mail to:
[email protected]
V.
Marcu,
M.C.
Coman,
Department of Radiology,
Emergency Hospital for Children M.S.
Curie,
20 Bd.
C-tin Brancoveanu,
Bucharest,
Romania.
S.
Tarnoveanu,
S.
Stoica,
Department of Pediatric Neurosurgery,
Emergency Hospital for Children M.S.
Curie,
20 Bd.
C-tin Brancoveanu,
Bucharest,
Romania.
C.
Cirstoveanu,
Department of Neonatal Intensive Care Unit,
Emergency Hospital for Children M.S.
Curie,
20 Bd.
C-tin Brancoveanu,
Bucharest,
Romania.