Learning objectives
Brucellosis is a systemic infection,
caused by facultative intra-cellular bacteria of the genus Brucella that can involve many organs and tissues.
The spine is the most common site of musculoskeletal involvement,
followed by the sacroiliac joints.
The aim of this study is to describe the imaging features of Brucella Spondylodiscitis with emphasis on characteristic signs.
Background
Brucellosis is a disorder of worldwide distribution,
relatively frequent in Mediterranean countries,
in Middle East and parts of central and south America [1].
Brucellosis is a zoonosis caused in humans by one of four species of the Brucella genus: B.
melitensis,
B.
abortus,
B.
canis and B.
suis.
B.
melitensis is the most virulent and invasive [2].
Brucella organisms are found in the excreta of infected animals (urine,
stool,
milk and products of conception).
Human can be affected by direct contact with infected animals or...
Imaging findings OR Procedure details
Radiographic manifestations usually appear 3 weeks to 5 weeks after the onset of clinical symptoms.
The lower lumbar spine is the preferential location.
The focal erosions of the superior or inferior vertebral body angle (brucellar epiphysitis) are characteristic of brucellosis.
(Fig.
1).
Focal anterior or diffuse disc collapse is very frequent but late and moderate.
A vacuum phenomenon may be observed,
especially in the anterior part of the disc,
possibly secondary to ischaemic changes in the disc,
with subsequent necrosis (Fig.
1) [4].
Bone destruction...
Conclusion
Clinical and imaging features help to suspect this rare and potentially severe entity that requires a specific treatment. Only rapid and effective management may prevent irreversible neurological and bony complications.
Diagnostic confirmation relies on bacteriological and immunological studies.
References
[1] Harman M,
Unal O,
Onbasi KT.
Brucellar spondylodiscitis MRI diagnosis.
J Clin Imaging 2001; 25: 421–427.
[2] Turgut Tali E.
Spinal infections.
Eur J Radiol 2004; 50: 120–133.
[3] Resnick D (ed).
Diagnosis of bone and joint disorders.
3rd ed.
Philadelphia: Saunders,
1995; 4: 2448–2558.
[4] Sharif HS,
Clark DC,
Aabed MY.
Granulomatous spinal infections: MR imaging.
Radiology 1990; 177: 101–107.
[5] Al-Shahed MS,
Sharif HS,
Haddad MC,
Aabed MY,
Sammak BM,
Mutairi MA.
Imaging features of musculoskeletal brucellosis.
Radiographics 1994; 14: 333–348.