Inflammatory myofibroblastic tumor of the liver was first described in 1953 by Pack and Baker.
Different synonyms have been used in het literature; Inflammatory pseudotumor,
Xanthogranuloma type pseudotumor,
Plasma cell granuloma,
Histiocytoma and " Plasmacytoma".
the most used name is inflammatory pseudotumor. Inflammatory myofibroblastic tumor is a localized mass consisting of a fibrous stroma and chronic inflammatory infiltrates with a predominance...
Methods and Materials
Thirty three patients (18 male,
mean age 51 years) with histopathology proven IMT and CC from 1995- 2011 were included in the study population.
CT-scan was performed in 29 patients and MRI in 20 patients.
All examinations were read independently bytwo radiologists. The clinical finding,
lesion density/ signal intensity (SI),
dynamic contrast-enhanced characteristics and morphologic charcateristics (size,
bile duct compression and dilatation,
tumor extension in bile ducts...
IMT was proven in 14 (42%) patients and CC in 19 patients (57%). Clinical finding: IMT patients often present with fever (n=5,
35%),abdominal pain (n=6,
42%) and blood tests showed often elevated infection parameters ( 57%).
Patients with CC often present with painless jaundice (n=9,
47%) and with elevated liver enzyme in the bloodtests ( 79%). On imaging,
there is no obvious difference in lesion density or SI between IMT and CC.
Both entities show increasing enhancement during delayed phase....
Differentiating IMT from CC is a challenging clinically and on imaging No obvious difference in contrast enhancement characteristics (IMT/CC) Morphological imaging characteristics are important in differentiating IMT from CC
Lakshmana Das narla,
Radiographics 2003; 23: 719-929 Liang Tang et al,
Inflammatory myofibroblastic tumor of the liver: A cohort study.
Surg 2010; 34: 309-313 Gleason B.C,
Inflammatory myofibroblastic tumours: where are we now.
J Clin Pathol 2008; 61:428-437
Elias 1 ,
F. Willemssen 1 ,
K. Biermann 2 ,
P. Krestin 1 ,
R. Dwarkasing 1 1.
Department of Radiology 2.
Department of Pathology Erasmus MC - University Medical Center PO Box 2040 3000 CA Rotterdam The Netherlands E-mail: email@example.com