Learning objectives
Computerised Tomography (CT) & Magnetic Resonance Imaging (MRI) are the preferred neuro-imaging modalities in investigation of seizure disorders.
Accurate interpretation of CT & MRI examinations of brain requires an indepth understanding of various patterns of presentation of Cerebral Hemiatrophy associated with seizure disorders and their characteristic radiological features.
We propose to attend the following objectives-
To illustrate the diverse spectrum of pathologic conditions which commonly cause cerebral hemiatrophy.
To elucidate characteristic radiological findings in various conditions causing cerebral hemiatrophy for the establishment of diagnosis and...
Background
Cerebral Hemiatrophy (CHA) or unilateral brain atrophy is the end-stage of various pathologies culminating in atrophy or hypoplasia of a single cerebral hemisphere [9].
Cognitive derangement,
behavioural change,
hemiplegia,
seizures and emotional deficits are possible functional implications [16].
Radiologically,
there is cerebral hemiatrophy with contralateral thickening of calvarium ,
ipsilateral hyperpneumatization of paranasal air sinuses,
elevation of petrous ridge and associated parenchymal changes.
Cerebral hemiatrophy is infrequently encountered in paediatric clinical practice.
However it exists and could be primary or secondary.
The primary (congenital) CHA...
Findings and procedure details
Of 1800 CT & MR studies of the head over a period of six months,
five patients were found to have clinical & radiological evidence of cerebral hemiatrophy.
The Computerised Tomographic scans were performed on a 256-slice CT scanner,
while Magnetic Resonance studies were performed on a 1.5 Tesla MR System with multinuclear spectroscopic capabilities using standard head coils (circularly polarized phased array head coil).
Two cases of Dyke-Davidoff-Masson Syndrome revealed cerebral hemi-atrophy,
leading to dilatation of sulci and cisterns as well as ex-vacuo dilatation...
Conclusion
Neuro-imaging findings in conditions associated with cerebral hemiatrophy reflect the underlying gross pathologic changes that are the consequence of an atrophic or hypoplastic process that began in early developmental period,
caused by diverse etiologies.
Understanding the distinguishing radiologic features of diverse pathologies can assist in clinching the correct diagnosis and formulating a reasonable treatment protocol.
Personal information
Dr.
Vipin Kumar Bakshi,
Department of Radio-diagnosis & Imaging,
Mahatma Gandhi Medical College & Hospital,
Jaipur,
INDIA;
[email protected]
Dr Puneet Yadav,
Department of Radio-diagnosis & Imaging,
Mahatma Gandhi Medical College & Hospital,
Jaipur,
INDIA
Dr.
Jai Chowdhary,
Department of Radio-diagnosis & Imaging,
Mahatma Gandhi Medical College & Hospital,
Jaipur,
INDIA
Dr.
Hemant Kumar Mishra,
Department of Radio-diagnosis & Imaging,
Mahatma Gandhi Medical College & Hospital,
Jaipur,
INDIA
Dr.
Mohan Shivnani,
Department of Radio-diagnosis & Imaging,
Mahatma Gandhi Medical College & Hospital,
Jaipur,
INDIA
References
Akinkunmi,
M.,
Salisu,
M.,
& Awosanya,
G.
(2010).
Rasmussen Encephalitis in a Nigerian Child: A Case Report.
The Internet Journal of Radiology,
12(2)
Alpers B J and Dear R B,
Hemiatrophy of the brain,
J Nerv Ment Dis 1939; 89: 653-651.
Atalar MH,
Icagasioglu D,
Tas F.
Cerebral hemiatrophy (Dyke-Davidoff-Masson Syndrome) in childhood: clinic-radiological analysis of 19 cases.
Pediatr Int.2007 Feb;49(1):70-7.
Bien,
C.
G.,
Granata,
T.,
Antozzi,
C.,
Cross,
J.
H.,
Dulac,
O.,
& Kurthen,
M; et al (2005) Pathogenesis,
diagnosis
and treatment of Rasmussen...