To establish the role of 3T MRI as a diagnostic tool for prostate cancer and assessing its efficacy by correlating with the histopathological findings (considered as a gold standard) used as a reference standard to evaluate the efficacy of our findings on MRI Reviewing the current value of multiparametric MR imagingand PIRADS 2 for accurate localization and staging of prostatic cancer

Prospective study was conducted in the Department of Radiology at Breach Candy Hospital Trust, Mumbai. A total of 52 patients presenting with a high PSA with suspicion for prostatic carcinoma were included. Multiparametric evaluation includes T2W,DWI/ADC and DCE (Dynamic contrast enhancement) All the patients were scanned on 3T Magnetom Verio Seimens scanner using the 6 channel phased array body coil. All statistical calculations were done using computer programs Microsoft Excel 2007 and SPSS version 21 The patients’ serum creatinine levels were checked prior to the...

There isa direct correlation between the MRI findings and the histopathology findings. The sensitivity and specificity of T2 weighted imaging are 91.1% and 83.3%. The sensitivity and specificity of DWI/ADC are 92.1% and 98.1%. The sensitivity and specificity of DCE are 93.4% and 60.8%. The PPV and NPV of T2 weighted imaging are 84.4% and 90.4%. The PPV and NPV of DWI are 97.9% and 92.6%. The PPV and NPV of DCE are 70.1% and 89.9% In our study 17 patients (32.6 percent) revealed carcinoma...

Multiparametric MRI evaluation with priority to ADC/DWI in the peripheral zone, followed by T2W imaging and early contrast enhancement increases the sensitivity and specificity of detecting a prostatic carcinoma which should be followed by a targeted TRUS guided biopsy for histological confirmation. These findings are in accordance with the recommendations of PIRADS 2.0

1) Cornfeld DM, Weinreb JC. MR imaging of the prostate: 1.5T versus 3T. (2007) Magnetic resonance imaging clinics of North America. 15 (3): 433-48 2)Scialpi M, Falcone G, Scialpi P, D'Andrea A.Diagn Interv Radiol. 2016 May-Jun;22(3):297-8. doi: 10.5152/dir.2016.15598 3) PIRADS 2.0: what is new? Turkbey B, Choyke PL. Diagn Interv Radiol. 2015 Sep-Oct;21(5):382-4. doi: 10.5152/dir.2015.15099 4)Greer MD, Shih JH, Lay N, Barrett T, Kayat Bittencourt L, Borofsky S, Kabakus IM, Law YM, Marko J, Shebel H, Mertan FV, Merino MJ, Wood BJ, Pinto PA, Summers...