Keywords:
Pelvis, Genital / Reproductive system male, MR, MR-Diffusion/Perfusion, MR-Spectroscopy, Contrast agent-intravenous, Cancer, Neoplasia
Authors:
R. S. SHETTY1, A. Kohli2, A. Shetty3; 1MUMBAI, MA/IN, 2Mumbai/IN, 3Mumbai, Maharashtra /IN
DOI:
10.1594/ecr2018/C-2072
Methods and materials
- Prospective study was conducted in the Department of Radiology at Breach Candy Hospital Trust,
Mumbai.
A total of 52 patients presenting with a high PSA with suspicion for prostatic carcinoma were included.
- Multiparametric evaluation includes T2W,DWI/ADC and DCE (Dynamic contrast enhancement)
- All the patients were scanned on 3T Magnetom Verio Seimens scanner using the 6 channel phased array body coil.
- All statistical calculations were done using computer programs Microsoft Excel 2007 and SPSS version 21
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The patients’ serum creatinine levels were checked prior to the MRI study,
EGFR was calculated and contrast study was done for EGFR above 30
-
No other specific preparation was mandatory for MRI,
except for an empty urinary bladder prior to the scan,
to avoid fluid artifacts during the scan
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Fasting was not mandatory even though contrast study was done in majority of the patients
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Patients were questioned about presence of any metallic implants / prosthesis in the body.
The only absolute contraindication for study was cardiac pacemaker
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T2W(axial and coronal),
DW/ADC (axial),
DCE VIBE (axial) and T1W(axial) images were obtained
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In this study we used the PIRADS 2.0 system as a reference for evaluation and staging of tumor
PI-RADS 2.0 assesses the likelihood (probability) of clinically significant prostate cancer on a 5-point scale for each lesion as follows [2,3]:
- PI-RADS 1 – Very low (clinically significant cancer is highly unlikely to be present)
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PI-RADS 2 – Low (clinically significant cancer is unlikely to be present)
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PI-RADS 3 – Intermediate (the presence of clinically significant cancer is equivocal)
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PI-RADS 4 – High (clinically significant cancer is likely to be present)
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PI-RADS 5 – Very high (clinically significant cancer is highly likely to be present)