- To present and illustrate the imaging findings of splenic lesions in hematologic malignancies. - To review the differential diagnosis of these lesions and to make an essay structured imaging report.

Introduction The spleen is considered the ”forgotten organ” because of the nonspecific pathologies involving it1. Often ignored by the clinician and by the radiologist, splenic lesions can be the key finding in some of the patients. Also, given that overlapping features of splenic lesions on imaging studies is often, it is sometimes hard to determine the causative etiology of a given splenic pathology using imaging studies alone1, 4, 5. Epidemiology Most splenic lesions are detected incidentally, posing a challenge for both interpreting and referring physicians...

We designed a retrospective study which reviewed imaging findings in hematology-oncology patients with splenic involvement hospitalized in our clinic in the period covering 2011-2018. The CT and MRI findings were further sub-classified based on the patient’s disease and the accompanying splenic complications. Classification: Concerning the hematologic malignancies, many entities affect the spleen by: tumoral infiltrating immunosuppressive or hemostasis disorders hematopoiesis changes Among these, splenic implication is either specific or not, depending on the causative pathology and its complications1,4,5 Splenomegalyinonco-hematology is a current pattern and it...

Imaging investigations play a crucial role in the diagnosis of splenic lesions providing criteria to choose between surgical or medical management - multidisciplinary teams are usually involved. The interpretation of different imaging studies should take into account all of the essential elements needed for making a correct diagnosis; Posibility of different lesions type coexistance, makes the imaging diagnosis harder. Leukemia affects the spleen much less frequently than lymphoma, while the rest of oncohematological entities cause more frequent complicated lesions or extramedullary hematopoiesis. Most complications developed...

Dr.Andrei [email protected] Prof.Ioana [email protected] Radiology,Medical Imaging an Interventional Radiology Department Fundeni Clinical Institute

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