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ECR 2013 / C-0702
MSCT in GIST patients with hepatic metastases treated with new generation tyrosinkinase inhibitors: comparison between density and dimension.
Congress: ECR 2013
Poster No.: C-0702
Type: Scientific Exhibit
Keywords: Oncology, Abdomen, Gastrointestinal tract, CT, Contrast agent-intravenous, Staging, Cancer, Metastases, Monoclonal antibodies
Authors: A. Insalaco, G. Lo Re, F. Muscarneri, F. Patti, M. C. Galfano, L. La Grutta, T. V. Bartolotta, M. Midiri; Palermo/IT

Methods and Materials

In the period between April 2011 and March 2012 were evaluated CT scans of six women aged between 45 and 75 with GIST at an advanced stage with the presence of liver metastases. Criteria for inclusion were evidence of disease that was unidimensionally measurable with CT; failure of previous treatment; adequate hepatic, renal, and cardiac function. Exclusion criteria were renal insufficiency (serum creatinine greater than 2 mg/dL), pregnancy and documented allergic reaction to iodinated contrast agent. Patients were observed  by MSCT after c.m administration, before start of  TKI treatment and after 3 and 6 months. For each patient were identified at least 3 liver lesions as target. For each of them were measured the maximum diameter and the HU densitometric average values in venous phase (by positioning of at least 3 ROI).

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