|ECR 2019 / C-1914|
|NET: CT-imaging findings and pathophysiological correlation|
NETs are a rare and heterogeneous group of neoplasms, which are derived from APUD cells, the so-called amine precursor uptake and decarboxylation properties system, ubiquitously found in the digestive tract, in pancreas, respiratory system and producing serotonin and histamine-like substances.
It was O. Lubarsch, a German pathologist native of Berlin, et al  in 1888, at the University of Munich, who provided the first detailed description of a carcinoid tumor. He gave the description of ileal carcinoids, called “little carcinomata”, originating in the intestinal crypts of Lieberkühn.
Neuroendocrine cells have dense core granules that readily stain with silver stains (also called argentaffin cells) and similarity to neural cells (expression of synaptophysin, neuron-specific enolase and chromogranin A), with the absence of axons and synapses.
Thematically related posters
ECR 2019 / C-0923
One, No One and One Hundred Thousand: The Wide Spectrum of Hepatic Cystic lesions - Tips and Tricks for Differential Diagnosis