Aims and objectives
Retinoblastoma is the most common paediatric intraocular tumour.
It usually presents as leukocoria and strabismus in children between 1-5 years of age.
Around 47-58 percent of leukocoria cases in children are due to retinoblastoma,
making it the leading cause of white pupillary reflex1.
Though retinoblastoma is a life-threatening disease,
it is curable with early diagnosis and appropriate treatment.
Establishing the best management of retinoblastoma and differentiating it from other causes of leukocoria is imperative for preservation of visual function.
Persistent Hyperplastic Primary Vitreous (PHPV) is...
Methods and materials
Patient Population:
This study was conducted at Radiology Department of Foundation University Medical College / Fauji Foundation Hospital,
Rawalpindi,
Pakistan from January 2016 to September 2018.
A total of 56 suspected retinoblastoma patients,
31 males and 25 females,
within the age bracket of one month to ten years (mean age 3.11),presenting with leukocoria referred to the hospital by paediatric ophthalmologists were randomly selected.
Previously diagnosed patients of retinoblastoma coming for follow up scans were not included.
Data Acquisition:
MRI was done on 1.5 teslaToshiba Vintage...
Results
When comparing the findings of ultrasound and MRI,
diagnosis of PHPV by ultrasound is comparable to that of MRI.
Ultrasound was unable to detect only 1 case where retrolental membrane was visualized on MRI as shown in Table 01.
Ultrasound was able to detect 31 cases of orbital mass while the number of cases detected by MRI was 39 as shown in Table 02.
Ultrasound out performed MRI in detection of calcification as seen in Table 03 where 24 cases picked by ultrasound were not...
Conclusion
Ultrasound findings were comparable to that of MRI in patients of retinoblastoma and PHPV.
Ultrasound is a highly sensitive diagnostic tool for differentiating between the two diseases in paediatric leukocoria patients.
It can be used as a screening tool in resource poor settings having limited sophisticated imaging modalities for early diagnosis and management.
Personal information
Dr Kiran Fatima Farooq,
Associate Professor,
Radiology Department,
Foundation university Medical College,
Islamabad,
Pakistan.
[email protected]
Phone no; +923215070969
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Guidelines...