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ECR 2019 / C-2697
Dynamic PET Perfusion Imaging (DPPI) to Characterize Thoracic Tumors: A Phase I Assessment of Ultra-fast Digital PET as an Imaging Biomarker
Congress: ECR 2019
Poster No.: C-2697
Type: Scientific Exhibit
Keywords: Molecular imaging, Nuclear medicine, Oncology, PET-CT, Cancer, Biological effects
Authors: M. V. Knopp1, E. D. Miller2, K. Binzel1, T. M. Williams1, P. Kneuertz2, M. Welliver2, M. I. Knopp1, C. L. Wright1, J. Zhang1; 1Columbus, OH/US, 2Columbus/US

Methods and materials


Dynamic FDG PET/CT was performed prior to radiation therapy of advanced thoracic tumors (lung and esophageal) in 24 patients using a next-generation digital photon counting system (Vereos Philips, dPET).


DPPI was performed at the time of bolus injection of ~185 MBq FDG over a volume of interest for 15 min.


PET listmode data were reconstructed using a range of 1 sec/fr to 60 sec/fr.


Blinded review by two experienced PET readers and descriptive statistics were calculated for data analysis.


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