Aims and objectives
The aim of this study is to evaluate the accuracy of the combined fast magnetic resonance imaging (MRI) and diffusion kurtosis imaging (DKI) in the characterization and differentiation of the breast lesions.
Methods and materials
Subjects
We prospectively enrolled 44 consecutive diagnostic breast MRI scans.
DKI was applied as a part of our standard breast MRΙ protocol in combination with dynamic contrast enhanced (DCE) -MRΙ in all cases.
The referral indications were mostly two: preoperative local staging of the tumor and clarification of suspicious findings on conventional imaging (mammography,
ultrasound) or clinical examination.
Imaging Protocol
All patients were examined in a 1.5 Tesla (T) MR unit equipped with a four-channel dedicated double breast coil.
Consensus of the examined women was...
Results
Malignancy was diagnosed in 28 cases through the course of surgery and histological verification.
The remaining 16 lesions were categorized as benign; their majority (13 cases) underwent histology,
while 3 of them did not comprise tissue sampling,
but instead were followed up and found to remain stable for a time period exceeding 2 years.
The mean size of the breast lesions was 10.6 mm for the benign lesions and 32.2 mm for the malignant ones,
thus indicating that all lesions comprised in this series could...
Conclusion
There are a few articles recently published to show that FAST breast MRI,
with its ability to detect early neovascularity,
could potentially make a big impact on identifying biologically relevant cancers that are fatal and currently missed by screening [19].
On the other hand,
diffusion kurtosis imaging has been showed to have higher specificity than conventional diffusion-weighted imaging for the assessment of the benign and malignant breast lesions [20].
In our study we showed that Fast MRI protocol combined with DKI Kapp and Dapp parametric...
Personal information
Alexandra Christou,
MD consultant radiologist in Doncaster and Bassetlaw Hospital NSH Trust,
UK,
previously at Iaso Maternity Hospital,
Greece
email:
[email protected]
Bougias HaralabosB.Sc RT (MR) University Hospital of Ioannina,
Greece
email:
[email protected]
Veliou Konstantia MDconsultant radiologist in Chatzikosta General Hospital of Ioannina,
Greece
email:
[email protected]
Priovolos dimitriosB.Sc RT (MR)at Iaso Maternity Hospital,
Greece
email:
[email protected]
Ghiatas Abraham MD,
Professor radiologist,
Chief of the imaging department atIaso Maternity Hospital,
Greece
email:
[email protected]
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