ECR 2009 / C-303
Comparison of Intravenous (IV) Isosmolar Contrast (IOCM) vs. Intraarterial (IA) IOCM or Low Osmolar Contrast Media (LOCM): A Prospective Multicenter Trial.
Authors:
R. P. Karlsberg, S. V. Dohad, V. Multicenter Group; Beverly Hills, CA/US
DOI:
10.1594/ecr2009/C-303
Purpose
- There is conflicting opinion whether the CIN rate following IV contrast administration differs from IA administration and there may be also differences in CIN rates among various types of contrast media.
- The purpose of this report was to compare incidence of CIN between IV administration of iodixanol (IOCM) for contrast-enhanced computed tomography (CTA) and IA administration of iodixanol or low osmolar contrast media (LOCM) for IA digital subtraction angiography (DSA) in the same population of patients with suspected peripheral arterial occlusive disease (PAOD).
- The research was part of a Phase 3, open-label, multi-center study to evaluate the efficacy and safety of iodixanol-enhanced CTA compared with diagnostic IA-DSA.