ECR 2009 / C-303
Comparison of Intravenous (IV) Isosmolar Contrast (IOCM) vs. Intraarterial (IA) IOCM or Low Osmolar Contrast Media (LOCM): A Prospective Multicenter Trial.
Authors:
R. P. Karlsberg, S. V. Dohad, V. Multicenter Group; Beverly Hills, CA/US
DOI:
10.1594/ecr2009/C-303
Methods and Materials
Study Design:
- Patients with suspected PAOD underwent CTA with IV iodixanol. After a washout of 3 to 14 days, IA DSA was performed with the contrast agent chosen and administered according to the clinical practice standards at each site (Figure 1).
Fig.
- Serum creatinine (SCr) was measured pre-procedure and 24 ± 4 hours after the procedure in each phase.
Statistical Analysis:
- CIN was defined as a SCr increase ≥25% from baseline after 24 hours.
- The population included in analysis was patients with SCr values at both baseline and 24 hours. In the IA DSA phase, patients must also have had the specific contrast agent recorded. Patients who received both IOCM and LOCM for their IA DSA were grouped according to the agent administered at the highest volume.
- Categorical variables were compared with chi-square statistics. A p value <0.05 was considered statistically significant.