Keywords:
Interventional non-vascular, Percutaneous
Authors:
A. L. Grinberg1, A. Herman2, Y. Tovbin2, C. Brahmi1, U. Nevo1; 1Tel Aviv/IL, 2Beer Yaakov/IL
DOI:
10.1594/ecr2010/C-1896
Purpose
This study aimed to contribute to the scientific understanding of the physics of MRI of freezing and thawing processes.
We considered some of the basic MRI properties, which are temperature dependent. This is what made MRI the modality of choice for providing near-real-time visualization of both changing morphology and 3D temperature distribution maps during thermal-therapy procedures.
1. Investigate and model the effects of extreme thermal stress on tissue and their reflection in MRI parameters such as T1-1 relaxation rate.
2. Develop an optimized protocol for thermal ablation, considering thermal history and thermodynamic parameters (such as temperature extremes and duration, freezing/thawing rate and cycle number), as well as appropriate MRI protocol and parametric maps for monitoring cryotherapy.