Keywords:
MR-Diffusion/Perfusion, Bones
Authors:
R. Yorimitsu1, T. Miyati1, M. Hara2, Y. Shibamoto2, T. Minami1, H. Kan1, A. Kitanaka1, S. Mihira1; 1Kanazawa/JP, 2Nagoya/JP
DOI:
10.1594/ecr2011/C-0957
Purpose
1.Yeung et al described that fat degeneration of bone marrow related to osteoporosis,
i.e.,
low BMD,
was reflected by a decreasing apparent diffusion coefficient (ADC) [1].
In addition we earlier reported that the ADC was correlated with the BMD and fat fraction [2],
but the relation between the restricted diffusion of the water molecules and the trabecular bone structure was unclear.
On the other hand,
numerous studies indicated that the diffusion-weighted signal from a single voxel could be described as the sum of two exponential functions,
i.e.,
fast and slow diffusing components [3].
2.The purpose of our study was to clarify the relationship between those diffusing components and trabecular bone structure with an original phantom.