Keywords:
MR-Diffusion/Perfusion, Bones
Authors:
R. Yorimitsu1, T. Miyati1, M. Hara2, Y. Shibamoto2, T. Minami1, H. Kan1, A. Kitanaka1, S. Mihira1; 1Kanazawa/JP, 2Nagoya/JP
DOI:
10.1594/ecr2011/C-0957
Methods and Materials
Materials:
On a 1.5-T MRI,
single-shot diffusion EPI was used with b values of 0 to 3000 s/mm2, and a sensitivity encoding technique.
We obtained the signal decay with b from selected regions of interest within a trabecular bone phantom,
which consisted of seven sponges changing the interspace areas,
and dry vertebral bone in a container filled with pure water (Fig.1).
Methods:
Signal decays with b obtained from selected regions of interest (ROI) within a trabecular bone phantom were fitted with the following equation:
SI = SI0 [ffast exp(-b ADCfast)+ fslow exp(-b ADCslow)]
where SI0 was the signal intensity in the absence of diffusion-weighting gradients.
ffast and fslow were fractions of fast and slow diffusing water components.
ADCfast and ADCslow were ADC of the fast and slow diffusing water component,
respectively.