Keywords:
Bones, Haematologic, Oncology, Digital radiography, Experimental, Comparative studies, Haematologic diseases
Authors:
A. Moraux, B. DUTOUQUET, X. LELEU, M.-H. VIEILLARD, A. Cotten, N. Boutry; Lille/FR
DOI:
10.1594/ecr2011/C-0971
Methods and Materials
The EOS® system presents itself as a cabin of about 2 m3 (fig.1) with two orthogonal systems,
each made up of a X-ray tube and a detector.
This is a new modality of X-ray imaging with a fan-shaped beam of X-rays unlike conventional X-ray beam.
The patient is standing inside the cabin and images are made by scanning the patient from head to foot (Fig.2-4).
The EOS® system is based on a multiwire chamber technology (Prof.
Charpak G.,
Nobel Prize for Physics in 1992) using a new type of gas detector.
It allows an amplification of the conversion of photons into electrons,
improving the signal to noise ratio and reducing the dose required for image formation.
Benefits compared to radiographs are the following:
- Single scan,
- Very low radiation dose,
- Short acquisition time,
- And standing position.
The latter is very attractive in musculoskeletal pathology for studying static posture,
especially among children (because of the low radiation dose).
Our study received prior approval from our Ethics Committee.
Forty-five consecutive patients with MM (initial diagnosis and first relapse) were included in this prospective study.
All patients underwent EOS® examination (frontal and lateral views from skull to knees with optimized protocol: 100kV,
400mAs) and radiographs (skull,
spine,
pelvis,
femurs,
humeri,
ribs) on the same day and provided informed consent.
Each imaging modality was read in a random order by 2 reviewers independently for the detection of bone lesions (osteolytic lesions,
vertebral collapses).
Whole-body MRI was performed in case of disagreement between the 2 imaging modalities [3].
Radiation dose and technical comfort were also assessed.