Role of diffusion-weighted imaging (DWI) for the detection of hepatic metastases from neuroendocrine tumours, compared to gadolinium-enhanced, T2W MRI and arterial CT scan.

Congress:

ECR 2011

Poster Number:

C-1676

Type:

Scientific Exhibit

Keywords:

CT-Angiography, MR-Diffusion/Perfusion, Liver

Authors:

M. De Santis¹, A. Pecchi², F. Casari¹, P. Torricelli¹; ¹Modena/IT, ²carpi (mo)/IT

DOI:

10.1594/ecr2011/C-1676

DOI-Link:

https://dx.doi.org/10.1594/ecr2011/C-1676

Fig. 1

Fig. 2

Fig. 3: a: DW image (b=1000) shows two subcapsular hyperintense B group lesions in...

Fig. 4: a: DW image (b=1000) some hyperintense liver metastases. b: a-CT confirms the...

Fig. 5: False Positive case. a: two hyperintense lesions detected on DWI (b=1000) and...

Results

Arterial CT scans (a-CT) and MR images (DWI-EPI; THRIVE; T2W-SS-SPAIR) were evaluated by two radiologists, who independently assessed the number and dimension of liver neuroendocrine metastases, with an almost perfect interobserver agreement. Lesions were counted and divided into three dimensional groups: A (0-9.9 mm lesions); B (10-19.9 mm lesions); C (≥ 20 mm lesions). Of the 150 A group lesions assessed on a-CT, DWI, THRIVE and T2W-SS-SPAIR detected, respectively: 87, 72 and 37 lesions. Of the 57 B group lesions assessed on a-CT, DWI, THRIVE and T2W-SS-SPAIR detected, respectively: 58, 41 and 45 lesions. Of the 50 C group lesions assessed on a-CT, DWI, THRIVE and T2W-SS-SPAIR detected, respectively: 50, 47 and 46 lesions. Totally, of the 257 lesions, DWI, THRIVE and T2W-SS-SPAIR detected, respectively 195, 160, 128 lesions (Fig. 1). For the detection of group A lesions, Sensitivity of DWI, THRIVE and T2W-SS-SPAIR was, respectively: 57% , 48%, 24%; PPV: 98%, 100%, 95%; Accuracy: 56%, 48%, 24%. For the detection of group B lesions, Sensitivity of DWI, THRIVE and T2W-SS-SPAIR was, respectively: 98% , 79%, 72%; PPV: 97%, 100%, 100%; Accuracy: 95%, 79%, 72%. For the detection of group C lesions, sensitivity of DWI, THRIVE and T2W-SS-SPAIR was, respectively: 100% , 92%, 94%; PPV: 100%, 100%, 100%; Accuracy: 100%, 92%, 94%. Totally, Sensitivity of DWI, THRIVE and T2W-SS-SPAIR was, respectively: 74% , 63%, 48%; PPV was: 98%, 100%, 98%; Accuracy was: 73%, 63%, 48% (Fig. 2-5).