Keywords:
Ultrasound, Elastography, Urinary Tract / Bladder, Oncology
Authors:
J.-M. Correas1, A. KHAIROUNE2, A.-M. Tissier3, V. Vassiliu3, D. EISS3, O. Hélénon2; 1Paris Cedex 15/FR, 2Paris, Cedex 15/FR, 3Paris/FR
DOI:
10.1594/ecr2011/C-1748
Methods and Materials
21 patients presenting with increased PSA values (4-10 ng/mL) were prospectively enrolled after signing an informed consent form.
The prostate was studied using trans-rectal ultrasound (TRUS) with spatial compounded B-mode,
colour Doppler US (CDUS) and SWE on the Aixplorer system (Supersonic Imagine,
Aix-en-Provence,
France; transducer SE12-3).
Elasticity measurements and ratios between nodules and adjacent parenchyma were calculated.
Contrast-enhanced US (CEUS) was performed using low MI pulse subtraction after injection of 4.8-9.6 ml of SonoVue® (Bracco,
Milan,
Italy) using an Aplio XG system (Toshiba MS,
Nasu,
Japan).
Imaging findings were correlated to sextant prostate biopsies (n=12) and targeted biopsies on suspicious areas (n=2-6) detected at SWE and CEUS.
MRI with axial and coronal T2w acquisition,
axial T1w acquisition,
diffusion and dynamic contrast-enhanced MRI (Signa 1.5T and Discovery MR450,
GE HealthCare,
Milwaukee,
WI,
USA) was also evaluated.
The blinded analysis of the SWE acquisition was performed retrospectively from cineloops and frames.
Normal and abnormal patterns were matched with pathology results.