Keywords:
Breast, Oncology, Computer applications, Nuclear medicine conventional, Mammography, SPECT, Technology assessment, Diagnostic procedure, Cost-effectiveness, Tissue characterisation, Neoplasia, Calcifications / Calculi
Authors:
D. J. Wagenaar1, J. W. Hugg1, R. A. Moats2, S. Chowdhury1, B. E. Patt1; 1Northridge, CA/US, 2Los Angeles, CA/US
DOI:
10.1594/ecr2011/C-1898
Results
Comparison of Benefit/Risk
Addressing the concerns
An important paper was published in 2010 by Hendrick in which wholebody radiation dose concerns were voiced about BSGI and other nuclear medicine scans breast scans such as PEM [He 10].
O’Connor’s paper [Oc 10a] helped to put these concerns in perspective by calculating benefit/risk ratios of the various screening modalities based on the BEIR VII formalism described in Section 3. With the pixel size optimized at 1.6 mm,
the detection efficiency is 3.6 times greater than that which was obtained with the standard high sens hex-hole collimator. Further dose reductions can be realized with the dual-head system through software that combines the conjugate views and uses resolution recovery and denoising [Oc 10b]. Sidebar Figure 1 (Figure 6) shows that LumaGEM with low-dose collimation and software can achieve nearly the same level of wholebody dose equivalent as a full four view mammography study.