Keywords:
CT-Angiography, Cardiovascular system
Authors:
J. choi, W. KWON; Wonju/KR
DOI:
10.1594/ecr2011/C-2209
Results
We evaluate 43 stents in 39 patients.
Baseline clinical characteristics of the study population are summarized in Figure 1. The average time interval between stent implantation and MDCT coronary angiography was is 708.87 ± 388.67; MDCT coronary angiography and follow up conventional coronary angiography was 20.72 ± 7.78.
The site of stent implantation was: right coronary artery in 10(23.3%),
left anterior descending coronary artery in 25(58.1%),
left circumflex coronary artery in 7(16.3%),
and ramus intermedius artery in 1(2.3%).
Sensitivity,
specificity,
positive predictive value,
and negative predictive value to detect ISR using 64-MDCT were 60%,
100%,
100%,
and 95%,
respectively (Figure 2).
For the assessment of minimal lumen CSA and minimal stent CSA,
64-MDCT showed a good correlation with IVUS (r = 0.73 and 0.63,
p < 0.0001)(Figure 3).
But correlation of area stenosis (%) between 64-MDCT and IVUS was weak,
with a correlation coefficient of 0.29.
ROC analysis assesses whether minimal lumen CSA on 64-MDCT provide a good diagnostic accuracy to predict significant ISR.
The area under the ROC curve was 0.82 (p < 0.0001) for per-stent analysis,
indicating a high degree of agreement between 64-MDCT and IVUS for significant ISR (Figure 4).
An optimal cutoff value of 6.2mm2 on 64-MDCT would have yielded a sensitivity of 83.33% and a specificity of 72%.