Keywords:
Haemodynamics / Flow dynamics, Contrast agent-intravenous, Computer Applications-Detection, diagnosis, CT-Quantitative, CT, Spleen, Pancreas, Liver
Authors:
T. Kanda1, T. Yoshikawa2, Y. Ohno2, N. Negi2, N. Kanata2, D. Takenaka2, H. Koyama2, K. Kitajima2, K. Sugimura2; 1Kobe /JP, 2Kobe/JP
DOI:
10.1594/ecr2012/C-0435
Results
RESULTS
Hepatic Perfusion Parameters
These parameters showed no particular trend dual-input MS and DC methods (Fig.
2).
There was a significant difference in arterial perfusion fraction indual-input CM method (Fig.
3).
Splenic, Pancreatic,
and Gastric Perfusion Parameters
These parameters showed no particular trend in 3 single-input methods (Fig.
4-6).
SUMMARY
A significant difference was only found in compartment model method in the liver.
DISCUSSION
When using MS or DC methods,
abdominal CT perfusion can be performed with flexible CM injection protocols.
Previous Reports on Inj.
Protocol for CTP
Abdomen:
CM volume did not change blood volume,
blood flow,
and permeability surface in colorectal cancer.
(Goh V,
et al.
Clin Radiol)
Brain:
Increase of CM concentration improves peak enhancement.
(Silvennoinen HM,
et al.
AJNR 2007)
Smaller doses of CM resulted in lower cerebral blood flow with sampling intervals >2sec.
(Wiesmann M,
et al.
Eur Radiol 2008)
Higher injection rates of CM resulted in higher CBF.
(Hu CH,
et al.
Clin Imaging 2007)
There are no reports on effects of CM concentration on perfusion values.
Further assessments are needed to optimize injection technique.