Purpose
Purpose of this prospective sudy was to make correlation of radiologic with histopathologic diagnosis in cases with soft tissue musculoskeletal lesions.
Prior US-guided core needle biopsy,
the goal was to achive radiologic imaging diagnosis using all imaging modalities: Plain film,
Ultrasound (US),
computed tomography (CT),and magnetic resonance imaging (MRI).
Finaly,
the correlation of biopsy/surgical speciment histopathological diagnosesto bedone.
Methods and Materials
Prospectively 100 consecutive patients (53 male,
47 female,
median age 51 years) with musculoskeletal soft tissue mass underwent:
- ultrasonography (US);
- computed tomography (CT) and
- magnetic resonance (MRI).
Ultrasound–guided core needle biopsy was done in all patients.
From all lesions we obtained 3-5 speciments from the representative part of the tumor.
All were outpatients,
without any complication after interventions.
Fifteen MR imaging parameters and corresponding parameters on US and CT were evaluated for making radiologic diagnosis.
Multivariate logistic regression analysis was used for...
Results
From all 100 cases we have got 70 benign lesions:
- 53 casese of benign tumors and
- 17 cases of tumor-like lesions.
Malignant lesions were present in 30 cases:
- 26 of them were primary malignant tumors (Fig.2) and
- 4 cases were metastases (fig.4).
The overall imaging accuracy for benign tumors as well as malignant was 92%.
Nine cases (9%) were false positive:
- 4 benign tumors,
- one tumor-like lesion and
- 4 metastases.
False negative were two (2%) cases.
The correlation...
Conclusion
Combination of individual multimodalities imaging parameters improved radiologic imaging diagnosis in differentiation between benign and malignant soft-tissue musculoskeletal lesions.
US-guided core needle biopsy is recommended as the procedure of choice for obtaining representative specimen of soft tissue musculoskeletal tumors for histological examination because of its high diagnostic accuracy and low complication rate.
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