Keywords:
Interventional non-vascular, Lung, Computer applications, Percutaneous, Fluoroscopy, CT, Biopsy, Computer Applications-Virtual imaging, Dosimetry, Pathology, Tissue characterisation, Neoplasia
Authors:
C. Floridi, F. Fontana, A. M. Ierardi, G. DeMarchi, L. Nocchi Cardim, C. Pellegrino, G. Carrafiello, C. Fugazzola; Varese/IT
DOI:
10.1594/ecr2013/B-0531
Purpose
Image-guided percutaneous trans-thoracic needle biopsy is a recognized,
safe and accurate diagnostic technique for the evaluation of benignity or malignancy of pulmonary nodules [1;2].
However,
its success is dependant on nodule characteristics and operator technique and imaging.
Conventional computed tomography (CT) guidance has several limitations: radiation to the patient lack of three dimensional imaging and lack of real-time visualization unless CT fluoroscopy is used [3].
CT fluoroscopy is associated with significant operator exposure and dose not completely resolve the limitations of real time 3D image reconstruction [4].
Recently,
Cone-Beam CT (CBCT) imaging was developed.
CBCT offers more flexibility than conventional CT,
characterized by closed CT gantries,
in the orientation of the detector system around the patient.Cone-BeamCTis available in C-arm systems with a flat-panel detector integrated with a cone beam X-ray tube integrated in the C-arm enabling the operator to obtain CT-like images and fluoroscopy from the same machine.
CBCT navigation system overlays pre-acquired CBCT images on real-time fluoroscopy thus enabling the operator to navigate needle based on 3D data set with real-time fluoroscopy.
The aim of this study is to evaluate the feasibility of percutaneous transthoracic needle biopsy of pulmonary nodules under XperGuide-CBCT navigation guidance.