Keywords:
Neuroradiology brain, Head and neck, MR-Functional imaging, Neural networks, Mammography, Biopsy, Colonography MR, Comparative studies, Endocrine disorders, Lymphoma, Neoplasia
Authors:
Y. Zhao, X. Zheng, Q. Wang, M. Zhang; Hangzhou/CN
DOI:
10.1594/ecr2013/C-0847
Results
For each group,
we compared the BOLD signal obtained during performance of tactile,
movement,
and tactile-movement integration trials,
with that obtained during the corresponding period in the control condition.
We also conducted inter-group analyses.
Tactile tasks
Inter-group comparisons showed greater activation in the healthy control subjects compared with the PD patients in the bilateral somatosensory cortex (area 1/3),
the parietal lobe (area 7/31),
the left premotor cortex (area 6),
and the right visual cortex (area 19).
In contrast,
less activation was found in controls’ the bilateral frontal lobes (area 9/10/47) compared to the PD group (Fig 2).
Motor tasks
Inter-group comparisons showedsignificantly stronger activation in the healthy control in the right extrastriate visual cortex (MT/V5,
BA 18) and the caudate nucleus.
In contrast,
greater activation was observed in the PD in the bilateral frontal lobe (area 24/9/32) and right thalamus (Fig 2).
Tactile-motor integrate tasks
Controls demonstrated significant increase signal in the bilateral somatosensory cortex (area 40/2),
left extrastriate visual cortex (area 19,
37,
MT/V5),
thalamus,
and right cerebellum while performing tactile-motor integrate tasks .
The inter-group comparisons revealed increased activity in the right occipital lobe (area 18/19) in control subjects compared with the PD patients.
In contrast,
increased activation was observed in the PD group compared with controls in the bilateral frontal lobe (area 10/47).