Keywords:
Haemodynamics / Flow dynamics, Diagnostic procedure, MR, Neuroradiology brain, CNS
Authors:
M. A. Lucic, M. Bjelan, A. Ragaji, K. Koprivsek, S. Lucic, D. Kozarski, M. Spirovski, V. Njagulj, D. Kozic; Sremska Kamenica/RS
DOI:
10.1594/ecr2013/C-1130
Methods and Materials
The study included one hundred patients (59 males and 41 females,
age range 29 to 74 years),
divided into the experimental group consisted of 52 patients with CH,
and the control group consisted of 48 age-matching healthy volunteers without the hydrodynamic disorder (WHD).
In all patients we performed brain MRI on 1.5T imager (Avanto TIM,
Siemens,
Erlangen) by use of ECG retrospectively gated phase-contrast FLASH (Fast Low-Angle Shot) through-plane sequence with following technical parameters (TR 36.2 ms,
TE 10.4 ms,
FA 10°,
VE 10cm/s,
FOV 200,
slab 4mm,
matrix 256x256,
acq 1) positioned perpendicularly to the cerebral aqueduct,
later displayed and evaluated by multiple gated images in a closed-loop cinematographic (CINE) format (Fig.
1).
In order to quantify CSF flow parameters,
the acquired images were analyzed by the use of “Segment” (v.
1.8 R0931),
a comprehensive freely available software package for medical image analysis and cardiac image analysis13.
The region of interest (ROI) has been manually defined at the level of cerebral aqueduct (Fig.
2).
The obtained numerical values in the CH group were statistically processed in comparison with the values in the age-related group of healthy volunteers without the CSF hydrodynamic disorder (WHD).