Purpose
The aim of this study is to compare the performance of whole-body MRI including:the diffusion-weighted (DWIBS) and STIR imaging,
and whole bodypositron emission tomography and computed tomography inpatients diagnosed to have lymphoma.
Staging,
dynamic monitoring and evaluation of treatment effectiveness of lymphoproliferative diseases requires accurate assessment of affected lymph nodes and extra nodular lesions.
Exclusion of concomitant pathologies and evaluation of comorbide states may affect on treatment.
Whole-body MRI may be useful in detecting systemic failures due to it’s high relative soft tissues contrast.
MRI...
Methods and Materials
Magnetic resonance imaging:
All studies were performed on full "Total imaging matrix "(Tim) MRI systems Siemens
MAGNETOM Espree 1.5T,
Verio 3.0T and Skyra 3.0T equipped with "Integrated Parallel Acquisition Technique" (iPAT).
MRI study protocol:
The study protocol includes T2-weighted coronal HASTE (Half Fourier single shot Turbo Spin Echo technique) and for overwhelming signal from adipose tissue 3D STIR (Short TI Inversion Recovery) images from the vertex to the proximal third of the leg capturing the whole body in the anterior-posterior direction.
Also diffusion-weighted images in...
Results
40 patients of the first two groups were carried out contrast enhanced CT of the chest,
abdomen and pelvis at least once - in case of mediastinal form of lymphoma only chest CT was performed in follow-up (in case of absence of vascular involvement in the pathological process suspicion contrast enhancement has not been administered).
Whole-body PET was performed in 20 patients of the first 2 groups.
In case of lesions in only one or more contiguous groups of peripheral lymph nodes,
the treatment control...
Conclusion
DWI can't be used as an independent method of diagnosis,
but it complements conventional MRI in lymphomas patients.
At the same time,
we note that to refine the nature of the lesion sighting study,
with optimal for the intended type of lesion diagnostic methods,
should be hold.
MRI of the whole body can also be used as a screening method in oncology even in patients without cancer history.
Compared with PET MRI advantages are a clear reflection of the anatomical structures,
exact location of the...
References
Gerwin Schmidt,
Dietmar Dinter,
Stefan Schoenberg Whole-body MRI chapter in Clinical MR-imaging (2010)
Ruth Eichner,
Klaus Wörtler,
Markus Essler,
Martina Rudelius,
Christian Peschel,
Ingo Ringshausen,
Katharina GötzeSymmetric multifocal bone marrow involvement diagnosed by whole-body magnetic resonance imaging in a patient with B lymphoblastic lymphoma.
Ann Hematol (2013)
Thomas C.
Kwee,
Taro Takahara,
Malou A.
Vermoolen,
Marc B.
Bierings,
Willem P.
Mali,
Rutger A.
J.
Nievelstein Whole-body diffusion-weighted imaging for staging malignant lymphoma in children.
Pediatr Radiol.
2010
Schmidt G,
Reiser M,
Baur-Melnyk A.
Whole-body MRI...
Personal Information
Azat Mikhaylov
Radiology,
Russian Medical Academy of Postgraduate
Education,
Moscow,
RUSSIAN FEDERATION
[email protected]