Keywords:
Cirrhosis, Diagnostic procedure, MR, Cardiac
Authors:
G. Gentile1, G. Mamone1, G. Marrone1, D. Filì2, C. Falletta2, F. Clemenza2, A. Luca1; 1Palermo/IT, 2Palermo, ITALY/IT
DOI:
10.1594/ecr2013/C-1856
Results
In baseline conditions,
there were not significant differences in cardiac index (CI) [p=0.56],
stroke volume (SV) [p=0.44],
end diastolic volume (EDV) [p=0.42],
EF [p=0.11],
E/A ratio [p=0.62] and deceleration time (DT) [p=0.45] between TIPS group and control group (TABLE 2).
Table 2: Baseline MRI and ECHO parameters
No patient showed late gadolinium enhancement of the myocardium.
Diastolic dysfunction was detected both in advanced cirrhosis (baseline condition) and in compensated cirrhosis (control group).
In TIPS group,
5 patients had E/A < 1 and 8 patients had prolonged (>200 ms) DT.
In control group 2 patients had E/A < 1 and 3 had prolonged (> 200 ms) DT.
After TIPS there was a significant increase in CI (from 3.4±0.6 to 4.2±0.5; p<0.05) and SV (from 46.0±10.2 to 57.1±11.8; p<0.05) whereas EDV [p=0.12] and EF [p=0.63] did not change significantly (TABLE 3,
Fig.
4-5).
Table 3: MRI and ECHO changes after TIPS placement
Fig. 4: Cardiac Index
Fig. 5: Stroke Volume
In post-TIPS condition one patient has shifted to E/A ratio < 1 and 2 patients has shifted to DT > 200 ms.
Whereas between pre and post-TIPS condition the mean of E/A ratio and DT not showed significant differences [p=0.99; p=0.79].