Type:
Educational Exhibit
Keywords:
Abdomen, Liver, Ultrasound physics, Elastography, Ultrasound, Technology assessment, Education, Cirrhosis, Pathology
Authors:
O. S. Jaffer, G. Yusuf, P. Sidhu; London/UK
DOI:
10.1594/ecr2013/C-1984
Conclusion
There is potential for replacing invasive methods of evaluation with non-invasive modalaties.
There has been significant progression in elatrography and all four modalities appear promising for the evaluation of liver fibrosis.
To further the development,
it would seem certain issues need consideration:
(i) The inherent inadequacies of the ‘reference standard’ of liver biopsy need to be addressed.
(ii) A universal protocol for image acquisition.
(iii) Prospective validation of cut-off values.
The advent of elastography is exciting,
both in its application and in its potential benefit for the patient.
However,
further studies are needed - particularly involving SSI.
Utilisation of these techniques has already led to a reduction in the need for biopsy.
It appears ultimately an integrated algorithm as an endpoint will allow a more streamlined and convenient patient experience.