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Keywords:
Abdomen, Liver, Elastography, Biopsy, Comparative studies, Diagnostic procedure, Cirrhosis
Authors:
B. Altiparmak, M. S. NURAL, R. Aydın, M. Danaci; Samsun/TR
DOI:
10.1594/ecr2014/C-0347
Results
The study included 59 cases (29 women,
30 men,
average age 45±15 years) who had percutaneous liver biopsy.
As a result of the histopathological assessment,
6 (%10.2) of the cases were reported to be F0,
28 (%47.5) of the cases were reported to be F1,
20 (%33.8) of the cases were reported to be F2 and 5 (%8.5) of the cases were reported to be F3.
Average strain rates were as follows for VPR; F0 (2.83 ± 0.45),
F1 (3.78 ± 0.47),
F2 (4.69 ± 0.46),
F3 (7.78 ± 1.63) while average strain rates were as follows for MPR; F0 (2.60 ± 0.49),
F1 (3.67 ± 1.18),
F2 (5.07 ± 0.9),
F3 (6.39 ± 2.86).
The strain values for VPR were between 2.32-10.07 while the strain values for MPR were between 1.93 and 10.28.
6 patients who did not have fibrosis had an average VPR of 2.83 and an average MPR of 2.60 while 53 patients who had fibrosis had an average VPR of 4.50 and an average MPR of 4.46 (p<0.001).
When the threshold value was chosen as 3.23 for VPR,
sensitivity was %96.2 and specificity was %83.3 (p<0.001); when the threshold value was chosen as 3.01 for MPR,
sensitivity was %88.7 and specificity was %83.3 (p<0,001).
ROC analysis which was used to determine the best threshold strain rates in all stages showed that AUC values were VPR 0.95,
MPR 0.92 for F≥1; VPR 0.94,
MPR 0.92 for F≥2 and VPR 1.00,
MPR 0.76 for F=3. When the concordance between VPR and MPR was assessed,
Spearman’s Correlation Coefficient was 0.75 and a high positive concordance was found between VPR and MPR (p<0.001).