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Keywords:
Cardiac, Cardiovascular system, Contrast agents, CT, CT-Angiography, Complications, Contrast agent-intravenous, Outcomes, Prostheses
Authors:
C. Schneider, A. Brumberg, F. Roller, J. Rixe, P. Roth, G. A. Krombach; Giessen/DE
DOI:
10.1594/ecr2015/B-0599
Methods and materials
Datasets from consecutive patients from April 2009 through September 2013 referred to MDCT and/or CCA for the purpose of TAVI evaluation were retrospectively analysed.
Patients were included when not on dialysis and when serum creatinine (SCr) was available before the first CM examination (baseline) and at least every 48 hours during the evaluation period (EP,
days between the first and the last CM examination or TAVI).
CI-AKI was defined and staged as shown in Figure 1 (Kidney Disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group,
2012) when CM exposure occurred within the prior 3 days.
Incidence of CI-AKI was correlated to potential risk factors: kidney function (estimated glomerular filtration rate,
eGFR),
heart failure (HF),
defined as left ventricular ejection fraction (LVEF) < 50%,
diabetes (DM),
amount of CM and duration of evaluation period (EP).
Multiple logistic regression was used for statistical analysis.